Genetic Data Contradicts Multiregional Hypothesis

  • Study 3 (small population size)

    • Nuclear Deoxyribonucleic acid: the chemical inside the nucleus of a cell that carries the genetic instructions for making living organisms.DNA The order of nucleotides in a DNA or RNA molecule, or the order of amino acids in a protein molecule.sequences

    • Alu Chromosomal abnormalities in which a DNA sequences are inserted into genes, disrupting the normal structure and function of those genes.insertions

    • HLA The regions of a gene that contain the code for producing a specific portion of a gene's protein.exons

    • Genetic material found in mitochondria, the organelles that generate energy for the cell.mtDNA mismatch distributions

    • frequency spectra ( Genetic material found in mitochondria, the organelles that generate energy for the cell.mtDNA, Y-chr)

    • allele size vs. homozygosity at tandem repeat Multiple places on a chromosome where specific genes or genetic markers are located, a kind of address for the gene.loci

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Slide 65 of 109


Seven independent measures of genetic diversity among human populations indicate that the founding human population must have been very small.1 This genetic evidence contradicts the multiregional hypothesis, which requires the presence of large interbreeding populations of hominids.


References Top of page

  1. Harpending, H.C., et al. 1998. Genetic traces of ancient demography. Proc. Natl. Acad. Sci. USA 95: 1961-1967.

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Last Modified June 21, 2006

 

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